Myopia can be associated with significant structural changes in the eye, including peripapillary atrophy, myopic macular degeneration and the enlargement and rotation of the optic disc (1). These were shown to impair the clinical assessment of cup-to-disc ratios, visual fields, and retinal nerve fiber layers (2), with increased odds of false positive glaucoma diagnoses (3).
While most traditional structural and functional tests are affected by these changes, macular ganglion cell-inner plexiform layer (GCIPL) hemifield test was shown to be relatively unaffected by the tilting of the optic nerve head seen in myopia (2), and Kim et al. have demonstrated its high sensitivity and specificity in diagnosing glaucoma in a context of high myopia (4). GCIPL hemifield test, however, is not yet commercially available for all optical coherence tomography devices.
Contributor: Kevin Gillmann – Moorfields Eye Hospitals, United-Kingdom
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