Tip of the Month
Publishing date: February 2018
Tip Editor: John Salmon
Tip reviewer: Roger Hitchings
The Science behind the Tip
It is well known that each patient has an individual circadian IOP pattern. Studies have shown that up to two thirds of the peak values are found outside office hours (1). IOP measurements seem to be more influenced by the body position than by the time of day: measurements taken in the sitting position do not vary significantly between night and day (2).
Fogagnolo et al (3) postulated that IOP measurements taken in the supine position during office hours could partially imitate the 24-hour IOP characteristics and should be integrated in the diagnostic procedures of glaucoma patients. Knowing the 24-hour IOP pattern of a patient is important because of the effect of long term IOP fluctuation on progression (4).
Contributor: Frances Meier-Gibbons - Eye Centre Rapperswil, Switzerland
1. Huang R, Ge J, Chen G, et al. Four measures of intraocular pressure fluctuation: which correlates most optimally with actual office-hour readings: J Glaucoma 2015; 24 : 550-555.
2. Lee Y, Kook N, Joe S et al. Circadian (24-hour) pattern of intraocular pressure and visual field damage in eyes with normal-tension glaucoma. Invest Ophthalmol Vis Sci 2012; 55 : 881-887
3. Fogagnolo P, Orzalesi N, Ferreras A, Rossetti L. The circadian curve of intraocular pressure: can we estimate its characteristics during office hours? Invest Ophthalmol Vis Sci 2009; 50- 2209-2215.
4. Caprioli J, Coleman AL. Intraocular pressure fluctuation: a risk factor for visual field progression at low intraocular pressures in the Advanced Glaucoma Intervention Study. Ophthalmology 2008; 115:1123-29.