This website uses cookies to help us give you the best browsing experience. By continuing to use this portal, you agree to our use of this tool.
To learn more about how we use cookies and how to manage them please read our notice here.
Journal Club
Clinical Paper of the Month - Exogenous influences on intraocular pressure
Exogenous influences on intraocular pressure

Publishing date: May 2019

Author(s): Kim YW (1), Park KH (2)

1 Ophthalmology, Seoul National University Hospital, Seoul, Republic of Korea.
2 Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea

Intraocular pressure (IOP), the pressure within the eyeball, is a function mainly of the production and elimination of aqueous humour. Balanced IOP helps to maintain the eyeball contour, allowing proper refraction of light in the anterior segment of the eye. Increases in IOP can cause injury to the ocular structure, typically the optic nerve head and retinal ganglion cells. IOP increase, additionally, is a risk factor for glaucoma progression. However, it is not unusual that glaucoma worsens despite well-managed IOP; indeed, glaucoma can develop and progress even within the normal IOP range. IOP measured once during daytime office hours might not provide sufficient information for effective glaucoma management.

In fact, IOP is not a fixed value but rather changes over time: it fluctuates with the intrinsic circadian rhythm and can also change in various lifestyle-related situations (eg, with body posture, during exercise, while holding breath and according to dietary habits). It is therefore worth exploring the various factors that can affect IOP and glaucoma risk. In this review, the various exogenous influences on IOP in the literature are investigated.

© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Br J Ophthalmol. 2019 Mar 25. pii: bjophthalmol-2018-313381. doi: 10.1136/bjophthalmol-2018-313381.

Keywords: glaucoma; intraocular pressure

Clinical Paper of the Month manager: Andreas Boehm

back to top