Journal Club archive
Here you can find all the previously published Journal Clubs.

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Risk Factors for Rapid Glaucoma Disease Progression (PDF) - Jul 2017 (clinical)

Interleukin-6 Deficiency Attenuates Retinal Ganglion Cell Axonopathy and Glaucoma-Related Vision Loss (PDF) - Jul 2017 (experimental)

Regulation of intraocular pressure by microRNA cluster miR-143/145 (PDF) - Jun 2017 (experimental)

Mitochondrial dysfunction in ocular disease: Focus on glaucoma (PDF) - Jun 2017 (clinical)

Restoration of Aqueous Humor Outflow Following Transplantation of iPSC-Derived Trabecular Meshwork Cells in a Transgenic Mouse Model of Glaucoma (PDF) - May 2017 (experimental)

Neuroprotection for glaucoma: Requirements for clinical translation (PDF) - May 2017 (clinical)

The pressure-induced deformation response of the human lamina cribrosa: Analysis of regional variations (PDF) - Mar 2017 (experimental)

The challenge of regenerative therapies for the optic nerve in glaucoma (PDF) - Mar 2017 (clinical)

New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics (PDF) - Feb 2017 (experimental)

Posner-Schlossman Syndrome (PDF) - Feb 2017 (clinical)

New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics (PDF) - Feb 2017 (experimental)

Posner-Schlossman Syndrome (PDF) - Feb 2017 (clinical)

Lamina cribrosa in glaucoma (PDF) - Jan 2017 (experimental)

Glaucoma Risk Alleles in the Ocular Hypertension Treatment Study (PDF) - Jan 2017 (clinical)

Glaucoma Risk Alleles in the Ocular Hypertension Treatment Study (PDF) - Jan 2017 (clinical)

Lamina cribrosa in glaucoma (PDF) - Jan 2017 (experimental)

The neuroprotective effect of latanoprost acts via klotho-mediated suppression of calpain activation after optic nerve transection (PDF) - Dec 2016 (experimental)

New classes of glaucoma medications (PDF) - Dec 2016 (clinical)

Steroid-induced ocular hypertension/glaucoma: Focus on pharmacogenomics and implications for precision medicine (PDF) - Nov 2016 (experimental)

Effectiveness of early lens extraction for the treatment of primary angle-closure glaucoma (EAGLE): a randomised controlled trial (PDF) - Nov 2016 (clinical)

Assessing the Association of Mitochondrial Genetic Variation With Primary Open-Angle Glaucoma Using Gene-Set Analyses (PDF) - Oct 2016 (experimental)

Monitoring ocular hypertension, how much and how often? A cost-effectiveness perspective (PDF) - Oct 2016 (clinical)

Glaucoma related Proteomic Alterations in Human Retina Samples (PDF) - Sep 2016 (experimental)

The Relative Odds of Progressing by Structural and Functional Tests in Glaucoma (PDF) - Sep 2016 (clinical)

Predegenerated Schwann cells-a novel prospect for cell therapy for glaucoma: neuroprotection, neuroregeneration and neuroplasticity (PDF) - Jul 2016 (experimental)

Importance of Normal Aging in Estimating the Rate of Glaucomatous Neuroretinal Rim and Retinal Nerve Fiber Layer Loss (PDF) - Jul 2016 (clinical)

Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma (PDF) - Jun 2016 (experimental)

Visual impairment and vision-related quality of life in the Early Manifest Glaucoma Trial after 20 years of follow-up (PDF) - Jun 2016 (clinical)

Diabetes, Triglyceride Levels, and Other Risk Factors for Glaucoma in the National Health and Nutrition Examination Survey 2005-2008 (PDF) - May 2016 (clinical)

The Potential of Human Stem Cells for the Study and Treatment of Glaucoma (PDF) - May 2016 (experimental)

Transplanted neurons integrate into adult retinas and respond to light (PDF) - Apr 2016 (experimental)

The Pathogenesis of Raised Intraocular Pressure in Uveitis (PDF) - Apr 2016 (clinical)

Rate and Pattern of Rim Area Loss in Healthy and Progressing Glaucoma Eyes (PDF) - Mar 2016 (clinical)

Retinal and Optic Nerve Damage is Associated with Early Glial Responses in an Experimental Autoimmune Glaucoma Model (PDF) - Mar 2016 (experimental)

Decreased Energy Capacity and Increased Autophagic Activity in Optic Nerve Axons With Defective Anterograde Transport (PDF) - Jan 2016 (experimental)

Microstructure of Peripapillary Atrophy and Subsequent Visual Field Progression in Treated Primary Open-Angle Glaucoma (PDF) - Jan 2016 (clinical)

Measurement of Systemic Mitochondrial Function in Advanced Primary Open-Angle Glaucoma and Leber Hereditary Optic Neuropathy (PDF) - Dec 2015 (experimental)

Trabeculectomy Can Improve Long-Term Visual Function in Glaucoma (PDF) - Dec 2015 (clinical)

Intraocular pressure reduction and neuroprotection conferred by bone marrow-derived mesenchymal stem cells in an animal model of glaucoma (PDF) - Nov 2015 (experimental)

Visual impairment and vision-related quality of life in the Early Manifest Glaucoma Trial after 20 years of follow-up (PDF) - Nov 2015 (clinical)

Association between Platelet Function and Disc Hemorrhage in Patients with Normal Tension Glaucoma: A prospective cross-sectional study (PDF) - Oct 2015 (clinical)

Soluble Tumor Necrosis Factor Alpha Promotes Retinal Ganglion Cell Death in Glaucoma via Calcium-Permeable AMPA Receptor Activation (PDF) - Oct 2015 (experimental)

In vivo imaging of axonal transport of mitochondria in the diseased and aged mammalian CNS (PDF) - Sep 2015 (experimental)

Patterns of Glaucoma Medication Adherence over Four Years of Follow-Up (PDF) - Sep 2015 (clinical)

Capsid Mutated Adeno-Associated Virus Delivered to the Anterior Chamber Results in Efficient Transduction of Trabecular Meshwork in Mouse and Rat (PDF) - Jul 2015 (experimental)

Relationship Between Daytime Variability of Blood Pressure or Ocular Perfusion Pressure and Glaucomatous Visual Field Progression (PDF) - Jul 2015 (clinical)

Structure-Function Relationship Between Bruch's Membrane Opening-Based Optic Nerve Head Parameters and Visual Field Defects in Glaucoma (PDF) - Jun 2015 (clinical)

In vivo dynamics of retinal microglial activation during neurodegeneration: confocal ophthalmoscopic imaging and cell morphometry in mouse glaucoma (PDF) - Jun 2015 (experimental)

Primary congenital glaucoma outcomes: lessons from 23 years of follow-up (PDF) - May 2015 (clinical)

GluA2 Trafficking Is Involved in Apoptosis of Retinal Ganglion Cells Induced by Activation of EphB/EphrinB Reverse Signaling in a Rat Chronic Ocular Hypertension Model (PDF) - May 2015 (experimental)

Lamina cribrosa depth in different stages of glaucoma (PDF) - Apr 2015 (clinical)

A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome (PDF) - Apr 2015 (experimental)

Facts and myths of cerebrospinal fluid pressure for the physiology of the eye (PDF) - Mar 2015 (clinical)

Characteristic patterns of dendritic remodeling in early-stage glaucoma: evidence from genetically identified retinal ganglion cell types (PDF) - Mar 2015 (experimental)

Neuroprotective effects of transcription factor Brn3b in an ocular hypertension rat model of glaucoma (PDF) - Feb 2015 (experimental)

Long-Term Follow-up in Preperimetric Open-Angle Glaucoma: Progression Rates and Associated Factors (PDF) - Feb 2015 (clinical)

Cumulative mtDNA damage and mutations contribute to the progressive loss of RGCs in a rat model of glaucoma (PDF) - Jan 2015 (experimental)

The impact of lack of government insured routine eye examinations on the incidence of self-reported glaucoma, cataracts and vision loss (PDF) - Jan 2015 (clinical)

Direct optic nerve sheath (DONS) application of Schwann cells prolongs retinal ganglion cell survival in vivo (PDF) - Dec 2014 (experimental)

Clinical outcomes in cytomegalovirus-positive posner-schlossman syndrome patients treated with topical ganciclovir therapy (PDF) - Dec 2014 (clinical)

Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process (PDF) - Nov 2014 (experimental)

Nocturnal systemic hypotension increases the risk of glaucoma progression (PDF) - Nov 2014 (clinical)

Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma (PDF) - Oct 2014 (experimental)

Optic Nerve Head Deformation in Glaucoma: The Temporal Relationship between Optic Nerve Head Surface Depression and Retinal Nerve Fiber Layer Thinning (PDF) - Oct 2014 (clinical)

Rates of retinal nerve fiber layer thinning in glaucoma suspect eyes (PDF) - Sep 2014 (clinical)

Artemin augments survival and axon regeneration in axotomized retinal ganglion cells (PDF) - Sep 2014 (experimental)

The effect of positional changes on intraocular pressure during sleep in patients with and without glaucoma (PDF) - Jul 2014 (clinical)

Optic Nerve Head Blood Flow Response to Reduced Ocular Perfusion Pressure by Alteration of Either the Blood Pressure or Intraocular Pressure (PDF) - Jul 2014 (experimental)

Three-year Treatment Outcomes in the Ahmed Baerveldt Comparison Study (PDF) - Jun 2014 (clinical)

Discovery and Functional Annotation of SIX6 Variants in Primary Open-Angle Glaucoma (PDF) - Jun 2014 (experimental)

Effect of Focal Lamina Cribrosa Defect on Glaucomatous Visual Field Progression (PDF) - May 2014 (clinical)

MMPs in the neuroretina and optic nerve: modulators of glaucoma pathogenesis and repair? (PDF) - May 2014 (experimental)

γ-Synuclein Antibodies Have Neuroprotective Potential on Neuroretinal Cells via Proteins of the Mitochondrial Apoptosis Pathway (PDF) - Apr 2014 (experimental)

Intraocular pressure fluctuation and glaucoma progression: what do we know? (PDF) - Apr 2014 (clinical)

Mitochondrial DNA Variant Discovery in Normal-Tension Glaucoma Patients by Next-Generation Sequencing (PDF) - Mar 2014 (experimental)

The Potential Association Between Postmenopausal Hormone Use and Primary Open-Angle Glaucoma (PDF) - Mar 2014 (clinical)

Emerging novel roles of neuropeptide Y in the retina: From neuromodulation to neuroprotection (PDF) - Feb 2014 (experimental)

The 5-Year Incidence of Bleb-Related Infection and Its Risk Factors after Filtering Surgeries with Adjunctive Mitomycin C: Collaborative Bleb-Related Infection Incidence and Treatment Study 2 (PDF) - Feb 2014 (clinical)

Regulation of Plasticity and Fibrogenic Activity of Trabecular Meshwork Cells by Rho GTPase Signaling (PDF) - Jan 2014 (experimental)

Relationship between Preferred Sleeping Position and Asymmetric Visual-field Loss in Open-angle Glaucoma Patients (PDF) - Jan 2014 (clinical)

Does optic nerve head surface topography change prior to loss of retinal nerve fiber layer thickness: a test of the site of injury hypothesis in experimental glaucoma (PDF) - Dec 2013 (clinical)

Anti-Connective Tissue Growth Factor Antibody Treatment Reduces Extracellular Matrix production in Trabecular Meshwork and Lamina Cribrosa cells (PDF) - Dec 2013 (experimental)

Pathogenesis and clinical implications of optic disk hemorrhage in glaucoma (PDF) - Nov 2013 (clinical)

Identification of retinal ganglion cell neuroprotection conferred by platelet-derived growth factor through analysis of the mesenchymal stem cell secretome (PDF) - Nov 2013 (experimental)

Lifetime Risk of Blindness in Open-Angle Glaucoma (PDF) - Oct 2013 (clinical)

Immune response against ocular tissues after immunization with optic nerve antigens in a model of autoimmuneglaucoma (PDF) - Oct 2013 (experimental)

The Ahmed Versus Baerveldt Study: Three-Year Treatment Outcomes (PDF) - Sep 2013 (clinical)

Onset and Progression of Peripapillary Retinal Nerve Fiber Layer (RNFL) Retardance Changes Occur Earlier than RNFL Thickness Changes in Experimental Glaucoma (PDF) - Sep 2013 (experimental)

Ocular Rigidity, Outflow facility, Ocular Pulse Amplitude and Pulsatile Ocular Blood Flow in Open AngleGlaucoma; a manometric study (PDF) - Jul 2013 (experimental)

Rho-associated kinase inhibitors: A novel glaucoma therapy (PDF) - Jul 2013 (clinical)

Prevalence and Severity of Undetected Manifest Glaucoma: Results from the Early Manifest Glaucoma Trial Screening (PDF) - Jun 2013 (clinical)

Acetylcholinesterase inhibition promotes retinal vasoprotection and increases ocular blood flow in experimental glaucoma (PDF) - Jun 2013 (experimental)

Reduction in Blood Glutathione Levels Occurs Similarly in Patients with Primary-Open Angle or Normal Tension Glaucoma (PDF) - May 2013 (experimental)

The eye and the heart (PDF) - May 2013 (clinical)

How Does Glaucoma Look?: Patient Perception of Visual Field Loss (PDF) - Apr 2013 (clinical)

Tissue engineering the retinal ganglion cell nerve fiber layer (PDF) - Apr 2013 (experimental)

Treatment Outcomes in Malignant Glaucoma (PDF) - Mar 2013 (clinical)

Discovery of novel human aquaporin-1 blockers (PDF) - Mar 2013 (experimental)

Protective effect of lipoic acid against oxidative stress is mediated by Keap1/Nrf2-dependent heme oxygenase-1 induction in the RGC-5 cell line (PDF) - Feb 2013 (experimental)

Association between Myopia and Glaucoma in the United States Population (PDF) - Feb 2013 (clinical)

A new safety concern for glaucoma treatment demonstrated by mass spectrometry imaging of benzalkonium chloride distribution in the eye, an experimental study in rabbits (PDF) - Jan 2013 (experimental)

Balance control in glaucoma (PDF) - Jan 2013 (clinical)

Factors that influence standard automated perimetry test results in glaucoma: test reliability, technician experience, time of day, and season (PDF) - Dec 2012 (clinical)

Dorsomedial/Perifornical hypothalamic stimulation increases intraocular pressure, intracranial pressure, and the translaminar pressure gradient (PDF) - Dec 2012 (experimental)

Retinal Vessel Caliber Is Associated with the 10-year Incidence of Glaucoma: The Blue Mountains Eye Study (PDF) - Nov 2012 (clinical)

Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma (PDF) - Nov 2012 (experimental)

Intraocular pressure magnitude and variability as predictors of rates of structural change in non-human primate experimental glaucoma (PDF) - Oct 2012 (experimental)

Longitudinal effect of topical antiglaucoma medications on central corneal thickness (PDF) - Oct 2012 (clinical)

Practical landmarks for visual field disability in glaucoma (PDF) - Sep 2012 (clinical)

siRNA Silencing of Gene Expression in Trabecular Meshwork: RhoA siRNA Reduces IOP in Mice (PDF) - Sep 2012 (experimental)

Structural and functional abnormalities of retinal ganglion cells measured in vivo at the onset of optic nerve head surface change in experimental glaucoma (PDF) - Jul 2012 (experimental)

The Relationship Between Statin Use and Open-Angle Glaucoma (PDF) - Jul 2012 (clinical)

Do patients with glaucoma have difficulty recognising faces? (PDF) - Jun 2012 (clinical)

IOP induces upregulation of GFAP and MHC-II and microglia reactivity in mice retina contralateral to experimental glaucoma (PDF) - Jun 2012 (experimental)

JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death (PDF) - May 2012 (experimental)

Prevalence of cognitive impairment, depression, and anxiety symptoms among older adults with glaucoma (PDF) - May 2012 (clinical)

Cerebrospinal fluid exchange in the optic nerve in normal-tension glaucoma (PDF) - Apr 2012 (experimental)

The effect of thin, thick, and normal corneas on Goldmann intraocular pressure measurements and correction formulae in individual eyes (PDF) - Apr 2012 (clinical)

Cataract surgery after trabeculectomy: the effect on trabeculectomy function (PDF) - Mar 2012 (clinical)

Multipotent Stem Cells from Trabecular Meshwork Become Phagocytic TM cells (PDF) - Mar 2012 (experimental)

A New Approach to Assess Intracranial White Matter Abnormalities in Glaucoma Patients Changes of Fractional Anisotropy Detected by 3T Diffusion Tensor Imaging (PDF) - Feb 2012 (experimental)

Outcomes of different management options for malignant glaucoma: a retrospective study (PDF) - Feb 2012 (clinical)

Vision deficits precede structural losses in a mouse model of mitochondrial dysfunction and progressive retinal degeneration (PDF) - Jan 2012 (experimental)

Optic nerve sheath diameter in normal-tension glaucoma patients (PDF) - Jan 2012 (clinical)

The Association between Glaucomatous and Other Causes of Optic Neuropathy and Sleep Apnea. (PDF) - Dec 2011 (clinical)

IOP-Induced Lamina Cribrosa Deformation and Scleral Canal Expansion: Independent or Related? (PDF) - Dec 2011 (experimental)

Shrinkage of the scleral canal during cupping reversal in children. (PDF) - Nov 2011 (clinical)

Identification of a Novel Locus for Autosomal Dominant Primary Open Angle Glaucoma on 4q35.1-q35.2. (PDF) - Nov 2011 (experimental)

24-Hour IOP Telemetry in the Non-human Primate: Implant System Performance and Initial Characterization of IOP At Multiple Timescales (PDF) - Oct 2011 (experimental)

Intraocular Pressure Control and Long-term Visual Field Loss in the Collaborative Initial Glaucoma Treatment Study (PDF) - Oct 2011 (clinical)

Activated retinal glia mediated axon regeneration in experimental glaucoma (PDF) - Sep 2011 (experimental)

Vision loss and recovery after trabeculectomy: risk and associated risk factors (PDF) - Sep 2011 (clinical)

During Glaucoma, {alpha}2-Macroglobulin Accumulates in Aqueous Humor and Binds to Nerve Growth Factor, Neutralizing Neuroprotection (PDF) - Aug 2011 (experimental)

Trans-lamina cribrosa pressure difference correlated with neuroretinal rim area in glaucoma (PDF) - Aug 2011 (clinical)

Ex vivo optical coherence tomography imaging of collector channels with a scanning endoscopic probe (PDF) - Jul 2011 (experimental)

Lifestyle and risk of developing open-angle glaucoma: the Rotterdam study (PDF) - Jul 2011 (clinical)

Risk factors for visual field progression in treated glaucoma (PDF) - Jun 2011 (clinical)

Distortion of axonal cytoskeleton: an early sign of glaucomatous damage (PDF) - Jun 2011 (experimental)

Elastic modulus determination of normal and glaucomatous human trabecular meshwork (PDF) - May 2011 (experimental)

The Relationship Between Components of Metabolic Syndrome and Open-Angle Glaucoma (PDF) - May 2011 (clinical)

Early Gene Expression Changes in the Retinal Ganglion Cell Layer of a Rat Glaucoma Model (PDF) - Apr 2011 (experimental)

A Randomized Trial of Brimonidine Versus Timolol in Preserving Visual Function: Results From the Low-pressure Glaucoma Treatment Study (PDF) - Apr 2011 (clinical)

Investigation of the Association between Helicobacter pylori Infection and Normal Tension Glaucoma (PDF) - Mar 2011 (clinical)

Imaging the aqueous humor outflow pathway in human eyes by three-dimensional micro-computed tomography (3D micro-CT) (PDF) - Mar 2011 (experimental)

Laminar and prelaminar tissue displacement during intraocular pressure elevation in glaucoma patients and healthy controls (PDF) - Feb 2011 (clinical)

Evidence for a role of angiopoietin-like 7 (ANGPTL7) in extracellular matrix formation of the human trabecular meshwork: implications for glaucoma (PDF) - Feb 2011 (experimental)

Intravitreal injections of neurotrophic factors secreting mesenchymal stem cells are neuroprotective in rat eyes following optic nerve transection (PDF) - Jan 2011 (clinical)

Reversal of retinal ganglion cell dysfunction after surgical reduction of intraocular pressure (PDF) - Jan 2011 (experimental)

Genetic architecture of open angle glaucoma and related determinants (PDF) - Dec 2010 (experimental)

Predicting visual function from the measurements of retinal nerve fiber layer structure (PDF) - Dec 2010 (clinical)

Canadian Glaucoma Study: 3. Impact of risk factors and intraocular pressure reduction on the rates of visual field change (PDF) - Nov 2010 (clinical)

Qualitative and quantitative morphologic changes in the vasculature and extracellular matrix of the prelaminar optic nerve head in eyes with POAG (PDF) - Nov 2010 (experimental)

Functional MRI signal changes in primary visual cortex corresponding to the central normal visual field of patients with primary open-angle glaucoma (PDF) - Oct 2010 (experimental)

Incidence of glaucomatous visual field loss: a ten-year follow-up from the Rotterdam Study (PDF) - Oct 2010 (clinical)

Anthropometric measures and their relation to incident primary open-angle glaucoma (PDF) - Sep 2010 (clinical)

Current approaches and future prospects for stem cell rescue and regeneration of the retina and optic nerve (PDF) - Sep 2010 (experimental)

Genome-wide association study of normal tension glaucoma: common variants in SRBD1 and ELOVL5 contribute to disease susceptibility (PDF) - Aug 2010 (experimental)

Effect of sleeping in a head-up position on intraocular pressure in patients with glaucoma (PDF) - Aug 2010 (clinical)

Mitochondrial damage in the trabecular meshwork of patients with glaucoma (PDF) - Jul 2010 (experimental)

Clinical classification of childhood glaucomas (PDF) - Jul 2010 (clinical)

Effect of patient's life expectancy on the cost-effectiveness of treatment for ocular hypertension (PDF) - Jun 2010 (clinical)

Metabolic vulnerability disposes retinal ganglion cell axons to dysfunction in a model of glaucomatous degeneration (PDF) - Jun 2010 (experimental)

Delaying Treatment of Ocular Hypertension: the Ocular Hypertension Treatment Study (PDF) - May 2010 (clinical)

Neuroprotective Effects of Intravitreal Mesenchymal Stem Cell Transplantation in Experimental Glaucoma (PDF) - May 2010 (experimental)

Episcleral Venous Pressure Responses to Topical Nitroprusside and N-Nitro-L-arginine Methyl Ester. (PDF) - Mar 2010 (experimental)

Simvastatin and Disease Stabilization in Normal Tension Glaucoma: A Cohort Study. (PDF) - Mar 2010 (clinical)

Cerebrospinal Fluid Pressure in Glaucoma A Prospective Study. - Feb 2010 (clinical)

Hemoglobin expression and regulation in glaucoma: insights into retinal ganglion cell oxygenation. - Feb 2010 (experimental)

Prediction of glaucomatous visual field loss by extrapolation of linear trends (PDF) - Jan 2010 (clinical)

Ocular hypertension impairs optic nerve axonal transport leading to progressive retinal ganglion cell degeneration (PDF) - Jan 2010 (experimental)

Increased likelihood of glaucoma at the same screening intraocular pressure in subjects with pseudoexfoliation: the Thessaloniki Eye Study (PDF) - Nov 2009 (clinical)

Complex antibody profile changes in an experimental autoimmune glaucoma animal model (PDF) - Oct 2009 (clinical)